The New York Stock Exchange (NYSE) settled significantly lower on Tuesday, after achieving large gains during the first session of the week on Monday.
The Dow Jones Industrial Index closed dropped nearly 397 points or 1.51% and closed at 25,890 points.
The S&P 500 index fell by 34.4 points or 1.08% to close at 3,145.32, ending its longest rising streak since December 2019.
The Nasdaq Composite index lost 0.86% and closed settled at 10,343.89 after it recorded a new all-time high as it closed at 10,433.65 on Monday.
The fall in Wall Street indices is due to concerns about the rising number of COVID-19 cases in the US, especially in the absence of major economic data.